Lipotope, Inc.
UNPRECEDENTED
INNOVATION THAT DELIVERS
ABOUT
Lipotope, Inc. has created a revolutionary technology that utilizes the body’s own delivery processes to efficiently (in seconds) transport compounds safely and rapidly across skin. The underlying technology is an innovative liposomal nanoparticle (aka lipid nanoparticle) that maintains its integrity in the absence of complex / costly phospholipids, lipid derivatives or toxic solvents and efficiently engages the body’s natural transport pathways. Traditional lipid nanoparticle manufacturing is often inefficient with a high failure rate. Lipotope has solved this major problem using two highly reproducible, scalable, and well controlled processes for their product manufacturing. Traditional lipid nanoparticles are also either unstable or shield their cargo from the body making dosing a challenge. Lipotope’s technology imparts extended shelf life (current products last up to 2 years) and high bioavailability of cargo.
THE INNOVATION
Transdermal drug delivery is a holy grail of medicine. A wide array of companies have attempted transdermal large molecule delivery and failed. This has been an elusive objective, sought after by so many, because it creates a myriad of therapeutic opportunities in metabolism (insulin), vaccines (protein, mRNA, and DNA), cancer, athletic performance, and pain management without the need for needles or a visit to the doctor. Dr. Michael Oda has created protein stabilized liposomes (PSLs), an extremely effective transport vehicle for transdermal drug delivery.
PSLs are advanced nanoparticles that utilize the body’s natural transport processes to rapidly convey compounds safely across skin. PSLs contain a proprietary protein that is a molecular key to the skin’s highly protective barrier properties. As a result, compounds associated with PSLs are rapidly and safely transported into the body. PSLs are based on natural processes and as a result, enhanced delivery and stability do not come at the cost of bioavailability, facilitating micro-dosing (1000-fold lower than standard dosing).
Micro-dosing elevates therapeutic benefit, while minimizing adverse effects. Additionally, PSLs can be tuned for highly localized or systemic delivery, because they can be programmed to rapidly self-destruct or maintain long term stability. Further, multiple modes of administration are available beyond transdermal, which include trans nasal, trans pulmonary, and parenteral. PSLs will revolutionize topical drug delivery with broad utility in athletic, cosmetic, medical, and recreational applications.
PIVOT
Our first product, Pivot® Topicals, is a cannabinoid-based topical pain relief formula. Pivot® combines advanced formulation chemistry with the natural pain-relieving properties of cannabinoids to create a one-of-a-kind topical that targets and eliminates intense inflammation-based pain. So arthritis, migraine, shingles, and fibromyalgia pain are eliminated in seconds with relief that lasts hours. Pivot®’s proprietary advanced formula attacks inflammation-based pain by engaging the body’s natural transport mechanisms, enabling rapid uptake and focused delivery. Pivot rapidly crosses the skin by hijacking processes for sweat production… but in reverse. So Pivot® enters the skin as fast as people can sweat. In addition, Pivot® uses only a fraction of the active ingredient other topicals require to achieve superior results, because Pivot targets pain like a laser beam, unlike other topicals that take a shotgun approach.
Scent
Free
Fast
Acting
Long
Lasting
Non-
Greasy
OPPORTUNITIES
Cosmeceuticals
Cosmeceuticals like retinoic acid and botox need to cross the skin to elicit their beautifying effects. Lipotope’s technology offers the potential to rapidly and painlessly deliver these and other cosmeceuticals, eliminating the need for needles or complex treatment regimens.
Oncology
Most oncology chemotherapies are delivered systemically for localized tumors. Localized transdermal delivery is a potential lifesaving approach, minimizing the deleterious effects of systemic chemotherapy.
Mood, Seizure & Sleep
Lipotope’s technology can transport therapies trans-nasally, creating the opportunity to address depression, seizures, insomnia, cancer, Parkinson’s Disease and even Alzheimer’s Disease. Our first white label has proven highly effective for patients with PTSD and anxiety related sleep issues providing a full night's rest.
Sports
Pivot®, when applied to athletes has consistently yielded a 10% improvement in performance by eliminating / minimizing lactic acid burn. This in turn has enhanced / eliminated recovery time, enabling athletes to perform at their peak consistently.
CONTACT
Inquiries
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Contact Us
Michael Oda, Ph.D.
Scott Benson, CEO
Lipotope, Inc.